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Intern - Discovery Modeling and Simulation (Year Round)

San Diego, California


Takeda fosters a collaborative and stimulating work environment filled with opportunity and the chance to make a difference in people's lives. It is a workplace driven by integrity, one of Takeda’s long-held values that extends to both the patients we serve and our employees who develop and deliver medicines. Across our company, Takeda employees bring together diverse strengths that together create a stronger whole.

As one of the world’s leading biopharmaceutical companies, Takeda is committed to bringing Better Health and a Brighter future to people worldwide. We aspire to bring our leadership in translating science into life-changing medicines to the next level, in our core focus areas; oncology, gastroenterology, neuroscience, rare diseases, plasma-derived therapies, and vaccines.

Takeda California generates highly disease-specific and patient-tailored transformative new medicines aligned with Takeda’s global market strategies through research in Gastrointestinal (GI), Neuroscience and Immunology. Takeda California’s team of experienced scientists and clinicians deliver on the needs of patients by blending its internal capabilities, global Takeda resources, and expertise and technology from best-in-class external partners. Takeda California has opened a new 165,000 square-foot building which is an external innovation and collaboration hub for San Diego.

We are a passionate team doing important work that impacts patients’ lives. If you are driven to create better health and a brighter future, join us!

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  • Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.

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Intern - Discovery Modeling and Simulation (Year Round)

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Job ID R0015648 Date posted 01/16/2020 Location San Diego, California

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Job Description


As an intern in Discovery M&S group at TCAL, under the direction of a senior modeling and simulation expert in the group, you will support development of a quantitative systems pharmacology (QSP) model of irritable bowel disease (IBD) through the following activities:

  • perform literature searches, collates and evaluates clinical and preclinical data
  • develop a database for QSP model parameterization and validation
  • build QSP model framework and assess its developability based on available data
  • develop QSP model


  • Help identify appropriate published and internal data (e.g. indications, dosages, clinical endpoints, biomarkers, pharmacokinetics, in vitro data, in vivo data, pharmacology model data) and verify their quality with members of Takeda Immunology group
  • Put together an IBD mathematical model structure with a list of required model parameters by working with members of the M&S group
  • Evaluate the ability to develop the model based on gathered data
  • Expected hours: 10 - 20 hours while school is in session; up to 40 hours during school breaks


  • Undergraduate student (third or fourth year students preferred) in good academic standing with a major in a quantitative field (engineering, science, etc)
  • Highly motivated with an interest in translational research, quantitative analysis, and mathematical modeling.
  • Course(s) on Systems of Differential Equations
  • Hands-on mathematical modeling experience
  • Tools: expertise with Microsoft Excel required, exposure to MATLAB preferred


  • None 


  • None 




San Diego, CA

Worker Type


Worker Sub-Type

Paid Intern (Fixed Term) (Trainee)

Time Type

Full time

Job ID R0015648

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