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Director, Global Medical Lead TTP and SCD (Location can be Zürich or Lexington, MA)

Lexington, Massachusetts, Zurich, Switzerland


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Director, Global Medical Lead TTP and SCD (Location can be Zürich or Lexington, MA)

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Job ID SR0048990 Date posted 05/06/2020 Location Lexington, Massachusetts; Zurich, Switzerland


The Global Medical Lead TTP and SCD (TAK755) will develop and execute the medical scientific development strategy, pre-launch planning and global medical launch planning for rADMATS13 (TAK755) in close collaboration with the GPT TAK755.


  • Work with the GMTL and other GMLs to develop and execute multi-year global medical strategy alignment for the specified Product/Disease Area, appropriately aligned with overall strategy and incorporating R&D functional Strategies (clinical, regulatory, HEOR, PV, compliance)
  • Work with the GMTL on the development and in-year implementation of the medical plan globally and/or support in year plan definition and implementation by US GD TA team
  • Supports execution of specific medical projects per global medical strategy
  • Serve as Hematology Medical representative on standing and project-based cross-functional teams
  • As needed provide medical review to promotional and non-promotional materials
  • Act as a company representative interacting with external scientific leaders, patient advocacy groups and/or regulatory authorities
  • Establish appropriate strategic partnerships with center of excellence and KOLs in areas of scientific interest


Support the development of global medical strategy and plans with alignment with Global Medical Team.

  • Work with GMTL and Global Franchise and Product Leads to develop global medical plans that include tactics to support key strategic imperatives for the disease area/band in both pre- and post-launch setting
  • As delegated by the GMTL, lead functional (e.g. publications, medical communications, medical information and medical training) plans supporting global medical strategy with alignment with Global where applicable
  • As delegated by the GMTL, collaborate with relevant business partners to ensure aligned and medically appropriate brand strategy, planning and execution
  • As delegated by the GMTL, participate in product development strategy and provide medical affairs and R&D inputs.

Implementation in-year global medical strategy

  • As delegated by the GMTL, directly implement plans and collaborate with Global Franchise and Product Leads, potentially including:
  • Development and implementation of medical pre- and post- launch plans for late-stage pipeline products or product label expansions
  • Providing medical leadership for scientific communications, including core scientific statements, standard responses, Phase IV plans and publications
  • Planning, designing and managing or participating in local, regional, national and global medical Advisory Boards including working with vendor(s) to ensure timely submission and approval in RnD select
  • Providing medical review of Investigator Initialed Research (KKR) proposals and other grans through the grant approval process
  • Managing the design and execution of clinical studies (phase IIb/IV, disease registries, HEOR studies, outcomes surveys, etc.)
  • Monitoring and communicating progress against medical plan; propose and implement initiatives as needed to adjust to disease area requirements
  • Conducting and ensuring timely medical review and approval of promotional and meeting materials as required per SOP
  • Serving as Hematology Medical respresentative on standing and project-based cross-functional teams Serving as Global Medical respresentative on standing and project based cross-functional teams.

Effective compliant collaborations with internal stakeholders (R&D, commercial, marketing, regulatory, legal, and compliance) and scientific exchanges with external stakeholders (KOLs and HCPs) in alignment with customer needs and medical strategy

  • Act as company medical respresentative to engage external scientific leaders, policy makers, patient advocacy groups and/or regulatory authorities
  • Per medical strategy, establish and/or enhance partnerships with key academic institutions and develop relationships with key academic institutions and develop relationships with key thought leaders
  • Per medical strategy, establish appropriate partnerships with KOLs in areas of scientific interest
  • Represent Medical Affairs in internal and external meetings and present data on product/disease area

Education and Experience

  • A Doctor Degree in Medicine, (MD), PhD or PharmD is required.
  • 8-10 years of related work experience in industry, clinical or research institution, preferably in Genetics, Metabolic or Hematology
  • Experience in Medical Affairs particularly Hematology is preferred
  • Experience in supporting brands or disease area levels in country regional or global organizations if preferred
  • Experience in other relevant disease areas of interest though clinical experience, bio-pharmaceutical experience or education may be considered.

Key Skills and Abilities

  • Demonstrated business acumen and operational skills
  • Ability to think strategically and tactically from a medical perspective about how to medically appropriately support the growth of the brand
  • Ability to work in a Global mindset environment, across diverse cultures
  • Ability to collaborate appropriately with Commercial functions
  • Ability to represent company’s interest in scientific forums as needed
  • Excellent written and verbal communication skills
  • Ability to manage teams and drive initiatives
  • Results orientation and accountability
  • Good analytic skills as applied to medical, scientific and technical information

Notice to Employment / Recruitment Agents:

Employment / Recruitment agents may only submit candidates for vacancies only if they have written authorization to do so from Shire, a wholly-owned subsidiary of Takeda’s Talent Acquisition department. Any agency candidate submission may only be submitted to positions opened to the agency through the specific Agency Portal. Shire, a wholly-owned subsidiary of Takeda will only pay a fee for candidates submitted or presented where there is a fully executed contract in place between the Employment / Recruitment agents and Shire, a wholly-owned subsidiary of Takeda and only if the candidate is submitted via the Agency Portal. Candidates submitted or presented by Employment / Recruitment Agents without a fully executed contract or submitted through this site shall not be deemed to form part of any Engagement for which the Agency may claim remuneration.

Job ID SR0048990

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