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Scientist, Assay Development-Cell Therapy

Cambridge, Massachusetts

Overview

Takeda fosters a collaborative and stimulating work environment filled with opportunity and the chance to make a difference in people's lives. It is a workplace driven by integrity, one of Takeda’s long-held values that extends to both the patients we serve and our employees who develop and deliver medicines. Across our company, Takeda employees bring together diverse strengths that together create a stronger whole.

As one of the world’s leading biopharmaceutical companies, Takeda is committed to bringing Better Health and a Brighter future to people worldwide. We aspire to bring our leadership in translating science into life-changing medicines to the next level, in our core focus areas; oncology, gastroenterology, neuroscience, rare diseases, plasma-derived therapies, and vaccines. The Greater Boston Area is headquarters to many of our Global and US business units.

We are a passionate team doing important work that impacts patients’ lives. If you are driven to create better health and a brighter future, join us!

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What makes a successful member of our team? Check out the traits we’re looking for and see if you have the right mix.

  • Collaborative
  • Strategic
  • Results Driven
  • Team Player
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  • Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.

  • Since 1781, the values of Takeda-ism (Integrity, Fairness, Honesty, and Perseverance) have guided everything we do—from decision-making to interacting with patients.

  • Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.

  • Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

  • A strong, borderless team, we strive together towards our priorities and inspiring mission.

  • Recognized for our culture and way of working, we’re one of only 13 companies to receive Top Global Employer® status for 2020.

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Scientist, Assay Development-Cell Therapy

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Job ID R0022983 Date posted 09/14/2020 Location Cambridge, Massachusetts

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Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist, assay development- Cell Therapy in our Cambridge, MA office.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

As a scientist, assay development - Cell Therapy working on the Pharm Science, Cell Therapy team, you will be empowered to build a world class cell therapy team.

POSITION OBJECTIVES:

The successful candidate will be responsible for developing analytical methods in supporting of the development of   T or NK cell therapies. This individual would shape the characterization strategies required for in depth process/product understanding and will be working closely with Discovery, Process Development, Translational and other teams.

POSITION ACCOUNTABILITIES:

  • Independently make plans and executes experiments to test CAR-T cells/ CAR-NK cells. 
  • Perform phenotypic and functional analysis of CAR-T/NK cells using multi-parameter flow cytometry and in vitro assays looking at phenotype, proliferation, cytokine secretion and target cell killing.
  • Develop and optimize new in vitro assays for testing CAR-T/NK function.
  • Coordinate in vivo studies and ex vivo analysis of CAR-T/NK cells.
  • Prepare study protocols, reports, technology transfer documentation, and regulatory documents for clinical trials.
  • Present study results at team or department meetings, to external partners or at conferences.
  • Understand project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional and external stakeholders.
  • Work collaboratively with other members from different teams and demonstrates independent, self-starting and supportive of team-based research and able to work effectively in a matrix organization.
  • Build and maintain relationships with key vendors and assists with technical aspects of vendor negotiations.

EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES AND SKILLS:

Required:

  • PhD in Immunology, Cancer biology, stem cell biology and biomedical engineering or related pharmaceutical science; 0+ years relevant industry experience
  • Master’s degree in Immunology, Cancer biology, biomedical engineering or related pharmaceutical science; 5-7+ years relevant experience
  • Excellent working knowledge of standard immunology assays used to characterize CAR T or CAR NK cell products.
  • Expertise in multi-color flow cytometry including intracellular staining, multiplexed luminescent readouts, in vitro killing assays, Elisa…
  • Experience with xCelligence or incuCyte platform is desirable.
  • Prove ability to coordinate with multiple researchers for scheduling and execution of complex experiments
  • Proactive and highly self-motivated with strong analytical and troubleshooting skills.
  • Excellent interpersonal communication and organization skills with the ability to work independently and in a fast-paced team environment

TRAVEL REQUIREMENTS:

  • May require approximately 5-10% travel.

WHAT TAKEDA CAN OFFER YOU:

  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine

Discover more at takedajobs.com

No Phone Calls or Recruiters Please.

Locations

Cambridge, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job ID R0022983

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