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Scientist II, Medicinal Chemistry

Boston, Massachusetts


Takeda fosters a collaborative and stimulating work environment filled with opportunity and the chance to make a difference in people's lives. It is a workplace driven by integrity, one of Takeda’s long-held values that extends to both the patients we serve and our employees who develop and deliver medicines. Across our company, Takeda employees bring together diverse strengths that together create a stronger whole.

As one of the world’s leading biopharmaceutical companies, Takeda is committed to bringing Better Health and a Brighter future to people worldwide. We aspire to bring our leadership in translating science into life-changing medicines to the next level, in our core focus areas; oncology, gastroenterology, neuroscience, rare diseases, plasma-derived therapies, and vaccines. The Greater Boston Area is headquarters to many of our Global and US business units.

We are a passionate team doing important work that impacts patients’ lives. If you are driven to create better health and a brighter future, join us!

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  • Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.

  • Since 1781, the values of Takeda-ism (Integrity, Fairness, Honesty, and Perseverance) have guided everything we do—from decision-making to interacting with patients.

  • Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.

  • Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

  • A strong, borderless team, we strive together towards our priorities and inspiring mission.

  • Recognized for our culture and way of working, we’re one of only 13 companies to receive Top Global Employer® status for 2020.

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Scientist II, Medicinal Chemistry

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Job ID R0022210 Date posted 08/20/2020 Location Boston, Massachusetts

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Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist II in our Cambridge, MA office.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Futureto people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

As a Scientist II working on the Medicinal Chemistry team, you will be empowered to apply emerging therapeutic modalities, such as small molecule RNA modulation and targeted protein degradation toward the development of medicines for oncology, neuroscience, GI, and rare diseases.


  • We are seeking a creative and highly motivated medicinal chemist, with 3-5 years of relevant industry experience, to help us enhance our capabilities and expertise in the application of emerging therapeutic modalities, such as small molecule RNA modulation and targeted protein degradation, toward the development of medicines for oncology, neuroscience, GI, and rare diseases.
  • Strong laboratory-based focus and experimental excellence is required for this position.
  • Candidate will be expected to interact and collaborate with scientists throughout the Takeda research organization, as well as external partners.


  • Design, synthesize, and characterize biologically active molecules with suitable drug-like properties, with a focus on emerging therapeutic modalities, such as RNA modulation and targeted protein degradation.
  • Act as key member of a multidisciplinary drug discovery project team, taking a leading role in the development of project strategy, and analysis and communication of complex data.
  • Work with chemistry leadership to define and implement strategies to enhance our capabilities in emerging therapeutic modalities, and apply them across the Takeda research organization.
  • Interface and collaborate with a diverse array of scientists within and outside of Takeda.


  • PhD. in organic chemistry, medicinal chemistry, or related discipline, with 3-5 years of industrial experience in medicinal chemistry, with significant experience with RNA modulation or targeted protein degradation.


  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

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Boston, MA

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Full time

Job ID R0022210

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